Medulloblastoma can be initiated by deletion of Patched in lineage- restricted progenitors or stem cells
Yang, Z.J., Ellis, T., Markant, S.L., Read, T.A., Kessler, J.D., Bourboulas, M., Schüller, U., Machold, R., Fishell, G., Rowitch, D.H., Wainwright, B.J., Wechsler- Reya, R.J. Cancer Cell 14(2):135-145 (2008) PMCID: PMC2538687 PDF
•Highlighed by Eberhart, C.G., Even Cancers want to commitment: Lineage identity and medulloblastoma formation, Cancer Cell, 14 (2): 105-107, 2008. PMCID: PMC4512647